Step II: Metabolite Production
After the biomimetic screen, you choose which metabolites to have synthesized, from just one to all of them. HepatoChem can produce metabolites in sufficient quantities for structure elucidation and biological profiling studies. To reduce your cost we can adapt the synthesis to your needs and produce strict necessary quantities. For more detailed information, see this overview of Metabolite Synthesis.
While microsomes have proven valuable as a predictive tool, their productive capabilities are limited. Biomimetic Chemistry, on the other hand, possesses the advantages of both chemistry and biology and is thus a much more efficient tool for metabolite synthesis.
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Through our revolutionary technology, HepatoChem enables cost effective testable quantities of metabolites in-house even at the earliest stages of drug discovery. This new capability, which enables affordable early metabolite toxicity testing, offers drug companies the opportunity to save millions each year through dramatically improved drug pipelines.