For more than a decade HepatoChem has been offering metabolite production services to the pharmaceutical industry. Our unique process provides reaction capabilities with chemical catalysts that mimic oxidative metabolism and glucuronidation.
See more about the advantages of our Biomimetic Chemistry approach here.
We also have designed a platform for CH functionalization including fluorination and alkylation reactions using photochemistry.
Additionally we provide support for metabolism study, bioanalysis and CMC.
Metabolite Production Support
- In-vitro stability study
- Metabolite identification
- Glucuronidation kit
- Metabolite synthesis
- Parent/Metabolite quantification
CMC Support
- Analytical Method Development
- Stability/solubility study
- Impurity study
Small Molecule Chemistry
- Late Stage Functionalization
- Purification
- Consulting
HepatoChem’s Advantages
- Turnaround time/Reactivity
- Flexibility
- Problem solving
- FTE or FFS contract
- Our Biomimetic Chemistry Approach
Equipment / Instrumentation
- LC/MS/UV: Waters Quattro/Agilent HPLC
- High Resolution MS: Thermo Q-Exactive
- Small molecule purification: Prep HPLC Varian/Grace
