For more than a decade HepatoChem has been offering metabolite production services to the pharmaceutical industry. Our unique process provides reaction capabilities with chemical catalysts that mimic oxidative metabolism and glucuronidation.

See more about the advantages of our BioMimetic Chemistry approach here.

We also have designed a platform for CH functionalization including fluorination and alkylation reactions using photochemistry.

Additionally we provide support for metabolism study, bioanalysis and CMC.

Metabolite Production Support

CMC Support

  • Analytical Method Development
  • Stability/solubility study
  • Impurity study

Small Molecule Chemistry

  • Late Stage Functionalization
  • Purification
  • Consulting

HepatoChem’s Advantages

Equipment / Instrumentation

  • LC/MS/UV: Waters Quattro/Agilent HPLC
  • High Resolution MS: Thermo Q-Exactive
  • Small molecule purification: Prep HPLC Varian/Grace