Suzuki-Miyaura Cross-Coupling Screening Kits

Our Suzuki-Miyaura Cross-Coupling Screening Kits are designed to conveniently investigate up to 32 reactions simultaneously. Suzuki-Miyaura reactions have been reported in the literature using a wide range of catalysts and reagents. Consequently, these reactions are highly substrate, solvent and base specific.

When a first attempt is unsuccessful, the endless combinations can make researching optimum reaction conditions overwhelming.

In order to facilitate the screening of common Suzuki-Miyaura reaction conditions, EvoluChem has released a series of high-throughput reaction screening kits combining common palladium sources, ligands and base combinations to achieve successful cross-coupling transformations.

Suzuki-Miyaura Cross-Coupling Screening Kits Protocol

The standard protocol is performed with 100 µl  substrates solution at 0.15M concentration, 10% catalyst and 2 base quivalents. Additional conditions can be investigated by changing the substrate concentration, or amount of base. You can choose between 2 different arrays of catalysts as well as between aqueous solutions of base or solid anhydrous bases.

1.  Prepare the substrate solution.

palladium catalysts

2.  Add to reaction vials containing the pre-weighed reagents and catalysts using a syringe.

3.  Place the reaction block on a standard stir/heat plate and set your reaction temperature.

chemistry screening kit

4 Suzuki-Miyaura Screening Kits Available:

2 Array Formats of 6 Catalysts and 4 Bases

  • contains bases in aqueous solution
  • Array Format of 6 Catalysts and 4 Bases
  • contains solid anhydrous bases premixed with the catalysts
  • Array Format of 6 Catalysts and 4 Bases

2 Array Formats of 8 Catalysts and 4 Bases

  • contains bases in aqueous solution
  • Array Format of 8 Catalysts and 4 Bases
  • contains solid anhydrous bases premixed with the catalysts
  • Array Format of 8 Catalysts and 4 Bases
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