Suzuki-Miyaura Cross-Coupling Screening Kits

Our Suzuki-Miyaura Cross-Coupling Screening Kits are designed to conveniently investigate up to 32 reactions simultaneously. Suzuki-Miyaura reactions have been reported in the literature using a wide range of catalysts and reagents. Consequently, these reactions are highly substrate, solvent and base specific.

When a first attempt is unsuccessful, the endless combinations can make researching optimum reaction conditions overwhelming.

In order to facilitate the screening of common Suzuki-Miyaura reaction conditions, EvoluChem has released a series of high-throughput reaction screening kits combining common palladium sources, ligands and base combinations to achieve successful cross-coupling transformations.

Suzuki-Miyaura Cross-Coupling Screening Kits Protocol

The standard protocol is performed with 100 µl  substrates solution at 0.15M concentration, 10% catalyst and 2 base quivalents. Additional conditions can be investigated by changing the substrate concentration, or amount of base. You can choose between 2 different arrays of catalysts as well as between aqueous solutions of base or solid anhydrous bases.

1.  Prepare the substrate solution.
2. Add to reaction vials containing the pre-weighed reagents and catalysts using a syringe.

3. Place the reaction block on a standard stir/heat plate and set your reaction temperature. 

4 Suzuki-Miyaura Screening Kits Available

2 Kits are available with a array format of 8 catalysts and 8 bases.

The kit HCK1003-01-001 contains bases in aqueous solution.

The kit HCK1003-01-005 contains solid anhydrous bases premixed with the catalysts.

2 Kits are available with a array format of 8 catalysts and 8 bases.

The kit HCK1003-01-002 contains bases in aqueous solution.

The kit HCK1003-01-003 contains solid anhydrous bases premixed with the catalysts.

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