Suzuki-Miyaura Cross-Coupling Screening Kits
Our Suzuki-Miyaura Cross-Coupling Screening Kits are designed to conveniently investigate multiple reactions simultaneously. Suzuki-Miyaura reactions have been reported in the literature using a wide range of catalysts and reagents. Consequently, often these reactions are highly substrate, solvent and base specific. When a first attempt is unsuccessful, the endless combination of reagent make the research of optimum reaction conditions overwhelming. In order to facilitate the screening of common Suzuki-Miyaura reaction conditions, HepatoChem has released a series of high-throughput reaction screening kits combining common palladium sources, ligands and bases combinations to achieve successful cross-coupling transformations.
Suzuki-Miyaura Cross-Coupling Screening Kits Protocol
The standard protocol is performed with 100 µl substrates solution at 0.15M concentration, 10% catalyst and 2 equivalents of base. Additional conditions can be investigated by changing substrate concentration, amount of base. you can choose between 2 different arrays of catalysts and between aquous solution of bases or solid anhydrous bases.
1. Prepare the substrate solution.
2. Add to reaction vials containing the pre-weighed reagents and catalysts using a syringe.
3. Place the reaction block on a standard stir/heat plate and set your reaction temperature.
4 Suzuki-Miyaura Screening Kits Available
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