C-H Fluorination Platform


 Your next drug could be one fluorine away™


Process Description:

HepatoChem has developed extensive expertise in screening organometallic catalytic systems. We have designed a panel of fluorination reaction condition that can be quickly surveyed for fluorination of your lead compound. The first step consists on identifying fluorinated analogues using LC/MS. Then the second step consists of producing the desired analogues in sufficient quantities for your project needs.

fluorination process
  • Fast fluorinated analogues production
  • Fluorination of inaccessible position
  • Block metabolism site
  • Improve permeability
  • Screen >100 fluorination conditions in one step using only a few mg quantities of your compound.
  • Wide selection of catalyst and fluorinating reagents
  • Generate diverse  fluorinated analogues.
  • 1 week turnaround time
  • Produce analogue in milligram to gram quantities
  • Titration of DMSO solution by CLND
  • Photochemistry
  • Scale from milligram to gram quantities

learn more about late stage fluorination here

for more information contact us at info@hepatochem.com