Newsletters

Photochemistry of earth-abundant metals

A recurring theme for many of our articles over the last few months is that there just isn’t enough iridium or ruthenium in the earth’s crust to do all of the photochemistry that we would like to perform at scale. Due to cost and the scarcity of these metals, the...

The impact of high-throughput catalyst screening in drug discovery

The recent trend of chemical catalysis centers and industry-academia partnerships has led to an influx of new reactions with direct applications for medicinal chemists1.  High-throughput experimentation (HTE) approaches have significantly lowered sample and time...

How do you handle hygroscopic salts?

Salts such as weak bases are omnipresent in organic chemistry. The conversion rate of a reaction can be greatly affected depending on the salt. While it is easy to weigh K2CO3 or Na2CO3. Because salts like Cs2CO3 or K3PO4 are hydroscopic salts, they are more difficult...

HepatoChem Spring 2012 Newsletter

Collaboration With Prof. Michael Pollastri on Lead Diversification HepatoChem Inc. and Prof. Michael Pollastri at Northeastern University initiated a collaboration on lead diversification of bioactive small molecules. The objective of this partnership is to discover...

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