How do you handle hygroscopic salts?

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Salts such as weak bases are omnipresent in organic chemistry. The conversion rate of a reaction can be greatly affected depending on the salt. While it is easy to weigh K2CO3 or Na2CO3. Because salts like Cs2CO3 or K3PO4 are hydroscopic salts, they are more difficult...

ACS Expo 2016 August 21st-23rd

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ACS Expo 2016 August 21st-23rd Please come visit HepatoChem Booth #338 at the 252nd American Chemical Society National Meeting & Exhibition to discover our new catalog of chemistry kits.   Late stage functionalization kits Alkoxylation and Acetoxylation Kits...

Magic methyl in medicinal chemistry

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Methyl groups are very common in drug molecules. As reported by Heike Schonherr and Tim Cernak1, more than half of the top-selling drugs contains a CH3. A simple substitution of a C-H with a methyl can increase the potency of a compound by more than 100-fold. The...

Buchwald palladium precatalysts

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Palladium based catalysis is the most used tool to perform the formation of C-C, C-O and C-N. There are many sources of palladium such as PdOAc2, PdCl2 or Pd2dba3. However the related methods do not always allow sufficient conversion. Palladium precatalysts is an...