A few weeks ago, we discussed the history of the Lucent360™, our new photoreactor for light and temperatures control for screen to scale, in both batch and flow. This month, we want to share a series of experiments that demonstrate the value...
A Brief History of a PhotoReactor We write from time to time here about the topics that we find interesting or humorous in the photoredox, visible-light photocatalysis and photochemical literature (or whichever term you might like best to describe...
A recurring theme for many of our articles over the last few months is that there just isn’t enough iridium or ruthenium in the earth’s crust to do all of the photochemistry that we would like to perform at scale. Due to cost and the scarcity of...
The attack of the photocatalytic microrobots! We have intended to write a bit about visible-light decomposition of contaminants for a while... so what better entry into the topic than a story about self-propelled autonomous microrobots that can...
A New Potent Photooxidant Pushing the limits of LED driven visible-light photocatalysis requires some creative thinking to get more redox potential out of the tools that are readily available to us. A recent report by Wickens and coworkers...
Spring is nearly here in Massachusetts. The snow has almost completely melted, and the days are getting longer. Soon the first flowers will bloom and some of those flowers are catalysts for photoredox cross-coupling reactions. Wait, what? File...
Year in review 2020. Let’s all agree to not look back. 20 papers for 2020 As the year comes to the close, we thought it was time to have a little fun and look back at the year in photochemistry. 2020 was a big year for us at HepatoChem under...
Multi-photon approaches to synthetic photochemistry expand the potential pathways to create more efficient and potentially safer reaction conditions. Wenger and coworkers recently published a fascinating in-depth review on multi-photon excitation...
Near-Infrared (NIR) Light Gaining Interest For most of the previous century, photochemistry invoked images of high-powered mercury lamps, intense UV light and classical reactions such as [2+2]-cycloadditions, cyclizations and radical rearrangements...
Electron Donor-Acceptor (EDA) Complexes in Photochemistry The photochemistry of Electron Donor-Acceptor (EDA) complexes provides a new option to create complex chemical structures (scaffolds) without the need for expensive photocatalysts like...
In recent years, amide coupling has become the most frequently used reaction in medicinal chemistry1. Found as the backbone of proteins, the amide bond is nominal formed by the condensation of a carboxylic acid and an amine. Due to a nearly...