Metabolic Stability Study

We perform In vitro metabolic stability study in liver microsomes or S9.

5 time points incubation for half-life and intrinsic clearance measurement.

 

Metabolite Identification

 

LC/MS analysis for metabolite identification and metabolism profiling.

LC/MS Chromatogram

 

MS/MS Fragmentation

 

MS/MS method development

MS/MS fragmentation of parent and metabolites for structure determination

 

Ebastine (parent)

 

Main metabolite (+16)

 

For more information please contact us.