Aminium Coupling Reagent Kit

Product overview:

The amide coupling kits are ideal tools for the optimization of amide bond formation. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed reagents. We offer pre-selected arrays of reagents and salts or custom arrays depending on your needs.

Aminium reagent kit:

Aminium salts are very efficient amide coupling reagents with quick reaction times and minimal racemization.  Aminium reactions proceed without the need for an additive, although reactions are often improved with their use. We included ethyl (hydroxyimino)cyanoacetate) which can improve reaction rate.

Kit Description:

The kit contains vials loaded with 10 µmol of 6 different coupling reagents and a stirring bar and two vials containing ethyl (hydroxyimino)cyanoacetate). Reaction can be performed from 0.2 M in 50 µl  to 0.05 M in 200 µl at 1/1 ratio acid and coupling reagent.

Catalog Ref# HCK1005-01-004 ; List price $299

 

Features:
  • 0.3 ml crimped vial with stirring bar.
  • Specifically designed reaction block (in the starter kit HCK1006-01-001)
  • Pre-weighed reagents
  • Temperature from 0°C to 50°C
  • Pre-designed or custom arrays available
  • Reagents are packaged under inert atmosphere
Kit contents:
Name CAS Number Quantity Amount
Reaction Vial HATU 148893-10-1

2x vial

10 µmol

Reaction Vial HBTU 94790-37-1

2x vial

10 µmol

Reaction Vial HCTU 330645-87-9

2x vial

10 µmol

Reaction Vial COMU 1075198-30-9

2x vial

10 µmol

Reaction Vial HDMC 1082951-62-9

2x vial

10 µmol

Reaction Vial HDMA 958029-37-3

2x vial

10 µmol

Reagent Vial ethyl(hydroxyimino) cyanoacetate

3849-21-6

2x vial

70 µmol

 

Protocol:

 

hck1005-01-004_process

 

Reagent Structures:

HATUCAS 148893-10-1

HATU
CAS 148893-10-1

HBTUCAS 94790-37-1

HBTU
CAS 94790-37-1

HCTUCAS 330645-87-9

HCTU
CAS 330645-87-9

COMUCAS 1075198-30-9

COMU
CAS 1075198-30-9

HDMCCAS 1082951-62-9

HDMC
CAS 1082951-62-9

HDMACAS 958029-37-3

HDMA
CAS 958029-37-3

Ethyl(hydroxyimino) cyanoacetateCAS 3849-21-6

Ethyl(hydroxyimino) cyanoacetate
CAS 3849-21-6

 

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