Carbodiimide Coupling Reagent Kit

Product overview:

The amide coupling kits are ideal tools for the optimization of amide bond formation. This enables to conveniently screen multiple reaction conditions simultaneously using pre-weighed reagents. We offer pre-selected arrays of reagents and salts or custom arrays depending on your needs.

Carbodiimide reagents kit:

A broadly applicable method for the formation of amide bonds uses carbodiimides such as DCC (dicyclohexylcarbodiimide) or DIC (diisopropylcarbodiimide) or EDC (N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide) for activation. We included ethyl (hydroxyimino)cyanoacetate) often used to avoid racemization.

Kit description:

The kit contains vials loaded with 10 µmol of coupling reagent (DCC, DIC and EDC) and a stirring bar and two vials containing ethyl (hydroxyimino)cyanoacetate). Reaction can be performed from 0.2 M in 50 µl  to 0.05 M in 200 µl at 1/1 ratio acid and coupling reagent.

Catalog Ref# HCK1005-01-002 ; List Price $299

 

Features:
  • 0.3 ml crimped vial with stirring bar.
  • Specifically designed reaction block (in the starter kit HCK1006-01-001)
  • Pre-weighed reagents
  • Temperature from 0°C to 50°C
  • Pre-designed or custom arrays available
  • Reagents are packaged under inert atmosphere
Kit contents:
Name CAS Number Quantity Amount
DCC 538-75-0

4x vial

10 µmol

DIC 693-13-0

4x vial

10 µmol

EDC, HCl 25952-53-8

4x vial

10 µmol

ethyl(hydroxyimino) cyanoacetate 3849-21-6

2x vial

50 µmol

 

Protocol:
hck1005-01-002_process

 

Reagent Structures:

 

DCC

DCC
CAS 538-75-0

DICCAS 693-13-0

DIC
CAS 693-13-0

EDCCAS 1892-57-5

EDC
CAS 25952-53-8

Ethyl(hydroxyimino) cyanoacetateCAS 3849-21-6

Ethyl(hydroxyimino) cyanoacetate
CAS 3849-21-6

 

For more information contact us at info@hepatochem.com